{"id":7651,"date":"2022-04-14T16:20:40","date_gmt":"2022-04-14T16:20:40","guid":{"rendered":"http:\/\/lonecandle.com\/?p=7651"},"modified":"2022-04-14T16:20:40","modified_gmt":"2022-04-14T16:20:40","slug":"time-for-an-operation-warp-speed-to-develop-pan-coronavirus-vaccines","status":"publish","type":"post","link":"https:\/\/lonecandle.com\/?p=7651","title":{"rendered":"Time for an Operation Warp Speed to Develop Pan-Coronavirus Vaccines"},"content":{"rendered":"\n<p>\n\n&#8220;Way back in May 2020, three researchers at National Institute of Allergy and Infectious Diseases (NIAID) published an&nbsp;<a href=\"https:\/\/www.nature.com\/articles\/s41541-020-0198-1.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">op-ed<\/a>&nbsp;in&nbsp;<em>Nature<\/em>&nbsp;arguing that with respect to developing universal coronavirus vaccines &#8220;the time to start is now.&#8221; As it turns out, the time to start for the NIAID was 15 months later when the agency got around to awarding three academic institutions a little over $36 million to&nbsp;<a href=\"https:\/\/www.nih.gov\/news-events\/news-releases\/niaid-issues-new-awards-fund-pan-coronavirus-vaccines\" target=\"_blank\" rel=\"noreferrer noopener\">research pan-coronavirus vaccines<\/a>&nbsp;in September 2021.<\/p>\n\n\n\n<p>The Trump administration&#8217;s&nbsp;<a href=\"https:\/\/catalyst.nejm.org\/doi\/full\/10.1056\/CAT.21.0001\" target=\"_blank\" rel=\"noreferrer noopener\">Operation Warp Speed<\/a>&nbsp;could serve as a much better model for&nbsp;<a href=\"https:\/\/reason.com\/2020\/11\/09\/pfizer-biontech-covid-19-vaccine-is-90-effective\/\" target=\"_blank\" rel=\"noreferrer noopener\">incentivizing<\/a>&nbsp;pharmaceutical companies to greatly speed up the development and deployment of the&nbsp;<a href=\"https:\/\/www.medscape.com\/viewarticle\/969826#vp_1\" target=\"_blank\" rel=\"noreferrer noopener\">candidate pan-coronavirus vaccines<\/a>&nbsp;on which some are currently working. In a recent op-ed in the&nbsp;<em>Los Angeles Times<\/em>, two immunologists&nbsp;<a href=\"https:\/\/www.latimes.com\/opinion\/story\/2022-03-20\/universal-covid-vaccine-research\" target=\"_blank\" rel=\"noreferrer noopener\">point out<\/a>&nbsp;that&nbsp;the global cost of the COVID-19 pandemic is an estimated&nbsp;<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2771764#:~:text=The%20estimated%20cumulative%20financial%20costs,domestic%20product%20of%20the%20US.\" rel=\"noreferrer noopener\" target=\"_blank\">$16 trillion<\/a>, compared to the cost of developing a typical vaccine at&nbsp;<a href=\"https:\/\/www.thelancet.com\/journals\/langlo\/article\/PIIS2214-109X(18)30346-2\/fulltext\" rel=\"noreferrer noopener\" target=\"_blank\">$1 billion<\/a>. They note that even a $10 billion vaccine is minuscule compared with the pandemic&#8217;s toll.<\/p>\n\n\n\n<p>Among the promising pan-coronavirus candidate vaccines are the Walter Reed Army Institute of Research&#8217;s&nbsp;<a href=\"https:\/\/www.cnet.com\/health\/a-universal-vaccine-to-end-covid-pandemics-its-in-the-armys-sights\/\" target=\"_blank\" rel=\"noreferrer noopener\">spike ferritin nanoparticle COVID-19 vaccine<\/a>; Osivax&#8217;s&nbsp;<a href=\"https:\/\/3pbio.com\/osivax-and-3p-team-up-to-develop-vaccine-against-variants-of-sars-cov-2\/\" target=\"_blank\" rel=\"noreferrer noopener\">nucleocapsid vaccine<\/a>&nbsp;targeting a protein widely prevalent among coronaviruses that is unlikely to mutate; and Inovio&#8217;s&nbsp;<a href=\"https:\/\/ir.inovio.com\/news-releases\/news-releases-details\/2021\/INOVIOs-Pan-COVID-19-Vaccine-Candidate-INO-4802-Induces-Broad-Immunity-Against-Major-Viral-Variants-in-Preclinical-Studies\/default.aspx\" target=\"_blank\" rel=\"noreferrer noopener\">DNA vaccine<\/a>&nbsp;encoding variant sequences of the spike proteins the virus uses to invade cells.&#8221;<\/p>\n\n\n\n<figure class=\"wp-block-embed-wordpress wp-block-embed is-type-wp-embed is-provider-reason-com\"><div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"Cg8FhqqpbQ\"><a href=\"https:\/\/reason.com\/2022\/03\/22\/time-for-an-operation-warp-speed-to-develop-pan-coronavirus-vaccines\/\">Time for an Operation Warp Speed to Develop Pan-Coronavirus Vaccines<\/a><\/blockquote><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Time for an Operation Warp Speed to Develop Pan-Coronavirus Vaccines&#8221; &#8212; Reason.com\" src=\"https:\/\/reason.com\/2022\/03\/22\/time-for-an-operation-warp-speed-to-develop-pan-coronavirus-vaccines\/embed\/#?secret=kvmzPR8Mhc#?secret=Cg8FhqqpbQ\" data-secret=\"Cg8FhqqpbQ\" width=\"600\" height=\"338\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe>\n<\/div><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Way back in May 2020, three researchers at National Institute of Allergy and Infectious Diseases (NIAID) published an op-ed in Nature arguing that with respect to developing universal coronavirus vaccines &#8220;the time to start is now.&#8221; As it turns out, the time to start for the NIAID was 15 months later when the agency got around to awarding three academic institutions a little over $36 million to research pan-coronavirus vaccines in September 2021.<\/p>\n<p>The Trump administration&#8217;s Operation Warp Speed could serve as a much better model for incentivizing pharmaceutical companies to greatly speed up the development and deployment of the candidate pan-coronavirus vaccines on which some are currently working. In a recent op-ed in the Los Angeles Times, two immunologists point out that the global cost of the COVID-19 pandemic is an estimated $16 trillion, compared to the cost of developing a typical vaccine at $1 billion. They note that even a $10 billion vaccine is minuscule compared with the pandemic&#8217;s toll.<\/p>\n<p>Among the promising pan-coronavirus candidate vaccines are the Walter Reed Army Institute of Research&#8217;s spike ferritin nanoparticle COVID-19 vaccine; Osivax&#8217;s nucleocapsid vaccine targeting a protein widely prevalent among coronaviruses that is unlikely to mutate; and Inovio&#8217;s DNA vaccine encoding variant sequences of the spike proteins the virus uses to invade cells.&#8221;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[13],"tags":[588,409,483,167,1193,1483,811,925,410],"class_list":["post-7651","post","type-post","status-publish","format-standard","hentry","category-article-share","tag-corona","tag-coronavirus","tag-covid-19","tag-government","tag-government-spending","tag-investment","tag-science","tag-vaccine","tag-vaccines"],"_links":{"self":[{"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/posts\/7651","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lonecandle.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=7651"}],"version-history":[{"count":1,"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/posts\/7651\/revisions"}],"predecessor-version":[{"id":7652,"href":"https:\/\/lonecandle.com\/index.php?rest_route=\/wp\/v2\/posts\/7651\/revisions\/7652"}],"wp:attachment":[{"href":"https:\/\/lonecandle.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=7651"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lonecandle.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=7651"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lonecandle.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=7651"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}