“People who disapprove of drugs want to end their use, but consumers have never demonstrated a willingness to comply. Sellers always arise to meet their demand. Drug innovation to evade prohibitionists, and making cocktails of those drugs, is inherently more dangerous than legal markets.”
…
“Singer attributes endless innovation in ever-stronger drugs and the rise in resulting overdoses to the competition between prohibitionists and illicit suppliers to outwit one another.
“The iron law of prohibition — ‘the harder the law enforcement, the harder the drug’—means we can expect more potent and dangerous forms of drugs to continue to arise,” he adds.
If you blend “more potent and dangerous forms of drugs” in “polysubstance use” (or just speedball it) you’re going to add risks on top of risks. The results can be tragic, but they’re less the result of drugs than they are of restrictions and prohibitions that inevitably drive consumers to seek intoxicants from illegal suppliers.”
…
“”Like opioids, which originally came from the poppy, meth started out as a plant-based product, derived from the herb ephedra. Now, both drugs can be produced in bulk synthetically and cheaply. They each pack a potentially lethal, addictive wallop far stronger than their precursors,” Hoffman wrote.
Why grow a crop in a field, which can be targeted for destruction by prohibitionists, when you can synthesize the active ingredients in a hidden laboratory that’s difficult to find and can be moved if necessary? And if you’re going to synthesize it, why not find ways to make it more concentrated so that large numbers of doses can be moved in compact shipments? You can always cut it at the distribution end and sell it in lower-concentration doses.
Unfortunately, illicit laboratories aren’t always as reliable as aboveboard ones and underground chemists aren’t necessarily as competent or diligent. When somebody screws up or just doesn’t care, it’s much harder to hold a criminal network to account than it is to go after a corporation that has a mailing address and a reputation to maintain. The end result, for the drug trade, is illness and death from intoxicants of unknown purity and potency, if the formulation was even safe to begin with.”
…
“People have always wanted to alter their consciousness in ways great and small. They will continue to want to get high no matter how much disapproval their activities draw from sober scolds. The only question is whether those getting high will acquire their intoxicants of choice from legal, responsible suppliers who have to maintain their brands and explain themselves in court, or from illegal suppliers who meet demand by any means necessary.”
https://reason.com/2023/11/15/the-monster-isnt-the-drug-its-the-prohibition/