“Trump conflates cocaine, which is produced mainly in Colombia and is often transported by sea, with fentanyl, which is produced in Mexico and overwhelmingly enters the United States in small packages by land over the southern border. According to data from the Centers for Disease Control and Prevention (CDC), fentanyl accounts for nearly 70 percent of drug-related deaths in the United States.
The National Center for Drug Abuse Statistics says two milligrams of fentanyl is a potentially lethal dose. Trump therefore seems to be assuming that each of the boats destroyed on his orders was carrying 50 grams of fentanyl. That is pretty large for a fentanyl shipment: Between 2018 and 2023, according to a recent study, most fentanyl powder seizures weighed less than 40 grams. Even so, 50 grams (less than two ounces) is not large enough that you would see “fentanyl all over the ocean” after blowing up a boat carrying it, which underlines the point that Trump’s fentanyl is imaginary.
Even if we join Trump in pretending that cocaine is fentanyl, his claim relies on two other fallacious assumptions. If those 50 grams of fanciful fentanyl had not been intercepted, he implicitly posits, they would have been delivered to 25,000 different American consumers, each of whom would have consumed his share in a single sitting, with fatal results. Trump also imagines, contrary to more than a century of experience with drug interdiction, that traffickers do not compensate for intercepted shipments by sending more. When drugs are seized or destroyed, he seems to think, the total supply available to Americans is reduced by that amount. If that were true, it would be hard to understand why Trump says drug interdiction is “totally ineffective.”
Leaving aside these inconvenient details, Trump’s account of what he is accomplishing by ordering the deaths of suspected smugglers, like Bondi’s estimate of lives saved by less lethal anti-drug efforts that Trump now concedes were “totally ineffective,” is impossible on its face. Last year, the CDC estimates, illegal drug use resulted in about 82,000 U.S. “overdose deaths.” By Trump’s account, he has somehow prevented more than four times as many drug-related fatalities by destroying a tiny portion of the total supply.
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Trump is trying to justify murder as self-defense, obscuring the immorality and lawlessness of his bloodthirsty anti-drug tactics. Trump’s unprecedented policy of killing suspected drug smugglers instead of arresting them—which has already become the new normal—simultaneously corrupts the mission of the armed forces, erasing the traditional distinction between civilians and combatants, and undermines long-standing principles of criminal justice, imposing the death penalty without statutory authorization or any semblance of due process. But he hopes his extravagant claims about hypothetical deaths prevented by intercepting imaginary fentanyl will distract the public from the actual deaths he is ordering.”
“Bondi’s most obvious mistake is equating potential overdoses with actual overdoses: She assumes that 258 million opioid-naive people would each have consumed two milligrams of fentanyl in one sitting. But Bondi also erroneously assumes that seizing 3,400 kilograms of fentanyl is the same as reducing U.S. fentanyl consumption by that amount.
That is obviously not true. Prohibition allows drug traffickers to earn a hefty risk premium, which gives them a strong incentive to find ways around any barriers the government manages to erect. Given all the places where drugs can be produced and all the ways they can be smuggled, it is not possible to “cut off the flow,” as politicians have been vainly promising to do for more than a century. The most they can realistically hope to accomplish through interdiction is higher retail prices resulting from increased costs imposed on drug traffickers.
That strategy is complicated by the fact that illegal drugs acquire most of their value close to the consumer. The cost of replacing destroyed crops and seized shipments is therefore relatively small, a tiny fraction of the “street value” trumpeted by law enforcement agencies. As you get closer to the retail level, the replacement cost rises, but the amount that can be seized at one time falls.
These challenges—which are compounded in the case of fentanyl, a highly potent drug that can be transported or shipped in small packages containing many doses—explain why interdiction never seems to have a significant and lasting impact on retail prices. From 1981 to 2012, according to the Office of National Drug Control Policy, the average, inflation-adjusted retail price for a pure gram of heroin fell by 86 percent. During the same period, the average retail price for cocaine and methamphetamine fell by 75 percent and 72 percent, respectively. In 2021, the Drug Enforcement Administration reported that methamphetamine’s “purity and potency remain high while prices remain low,” that “availability of cocaine throughout the United States remains steady,” and that “availability and use of cheap and highly potent fentanyl has increased.””
“In exchange for the delay of these tariffs, the Mexican government agreed to send 10,000 national guard troops to its northern border while Trump vowed to stem the flow of American firearms into Mexico. Canada, meanwhile, pledged to implement its 1.3 billion border security plan (which it had already enacted in December). Trump posted on his Truth Social platform that he was “very pleased with this initial outcome, and the Tariffs announced on Saturday will be paused for a 30 day period to see whether or not a final Economic deal with Canada can be structured.””
“The US and its allies have warned for years that Iran is developing pharmaceutical-based weapons in breach of the 1997 Chemical Weapons Convention, which bans the manufacture and use of “toxic chemicals,” defined as “chemical action on life processes [that] can cause death, temporary incapacitation or permanent harm to humans or animals.” Treaty signatories — including Iran — are obligated to destroy existing stockpiles.
Still, evidence suggests Iran is pursuing PBAs. “In 2014, Iran’s Chemistry Department of IHU [Imam Hossein University] sought kilogram quantities of medetomidine — a [veterinary] sedative it has researched as an aerosolized incapacitant — from Chinese exporters, according to a 2023 US State Department’s report. “The Chemistry Department has little history of veterinary or even medical research, and the quantities sought (over 10,000 effective doses) were inconsistent with the reported end use of research.”
In September 2023, Iranian anti-government hackers “posted confidential documents detailing an Iranian military university’s development of grenades meant to disseminate medetomidine,” the State Department said.
Of particular concern were references in Iranian literature to the 2002 Dubrovka incident, when Russian security forces pumped pharmaceutical-based gas — probably fentanyl or carfentanyl, another synthetic opioid vastly more potent — into a crowded Moscow theater to subdue Chechen rebels who had taken almost a thousand hostages. Commandos then stormed the building and killed the incapacitated rebels — but the gas also killed more than 130 hostages.”
“the vast majority of fentanyl brought into the U.S. is not carried by illegal immigrants or the result of porous borders: From 2019 to 2024, 80.2 percent of the people arrested at the border with fentanyl were U.S. citizens, according to David J. Bier, director of immigration studies at the Cato Institute.
And as NPR reported last year, “the vast majority of illicit fentanyl—close to 90%—is seized at official border crossings.””
“Those laws create a black market in which the composition and potency of drugs is uncertain and highly variable. They also push traffickers toward highly potent drugs such as fentanyl, which are easier to conceal and smuggle. As a result, drug users like Gentili typically don’t know exactly what they are consuming, which magnifies the risk of a fatal mistake. The “poisoning” that Peace and Caban decried therefore is a consequence of the policies they were proudly enforcing in this very case.”
“Vance is perhaps the GOP’s leading practitioner of responding to questions about Russia’s invasion of Ukraine by pivoting to Mexico and fentanyl. “What are we talking about?” he asked at a voter forum in February 2022 as the invasion was imminent. “We’re talking about a border 5,000 miles away between Ukraine and Russia. That’s what our leaders are focused on. If we had leaders half as concerned about their own border as they were about the Ukraine-Russia border, we would not have a border crisis in this country.””
“The cartels are now engaged in activities that make control over territory and local authorities a business imperative. Politicians and policemen are reluctant to stand up to them or are in their pockets. That helps explain why the Catholic Church stepped in to end the violence here. And Chilpancingo is the seat of the regional government, on the surface at least with the evident trappings of state authority. In the more remote hills around here and down to the Pacific coast around Acapulco, there are places run fully by the cartels. In nine municipalities they pick the mayor and police chiefs, according to a local security consultant who, out of fear for his safety, insisted we not use his name. Resistance is dangerous. Two years ago, in San Miguel Totolapan, the mayor and 20 other people were gunned down at his house and the town hall after defying a local cartel.
“The gangs love territorial control,” says Eduardo Guerrero, a former senior government security official who runs a consulting business. “You can do many kinds of business once you control territory. They seek political support. They intervene in elections aggressively. At the local level, we are losing sovereignty.””
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“Mexico’s criminal networks and their ability to whittle away at state power here present a national security threat to both Mexico and the U.S. These groups are growing in sophistication, corrupting state institutions and people, arming up and seeping into communities on both sides of the border. They pose a challenge to Mexico’s still fledgling democracy, at the federal level just 24 years old, and hence the stability of America’s southern neighbor. They have enabled a record number of migrants, mostly from other countries, to get north through Mexico. They’re responsible for tens of thousands of deaths in both countries. Some 26 per 100,000 people are killed in Mexico every year, the highest homicide rate among the world’s larger countries. Fentanyl, recently the most lucrative drug that the Mexican criminal groups traffic into the U.S., is responsible for the deaths of some 70,000 Americans every year.
Seen through the prism of violence there and its impact on the U.S., Mexico is the rich Afghanistan next door, a place where the central authorities have lost control over key territory to armed groups. Imagine if al Qaeda were killing that many Americans? “It may be the most important national security issue facing America, with the least amount of attention,” says Hank Crumpton, who ran the CIA’s covert operations in Afghanistan after 9/11 and works in security out of Texas. “I think of [the cartels] as enemies that exhibit in structure and behavior the same characteristics of terrorist networks and of an insurgency.”
Mexico’s narco-state problem matters for larger strategic reasons. Security is the biggest hurdle to Mexico fully becoming part of North America in more than a geographic sense — an economic and demographic engine for the region, and a strong and stable American ally in the global competition against China.
This more hopeful vision of Mexico can give you whiplash. The country is a daily contradiction. But put aside preconceptions and look even more closely at Mexico. The last couple decades have brought stunning violence — and stunning economic gains.”
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“If there was an easy solution, it would’ve been tried by now. The security expert Eduardo Guerrero, like some other experts on both sides of the border, says the Mexican authorities alone can’t handle the challenge from the cartels. “If we don’t stop them they will take over several key Mexican states at this rate,” he says. “We need help. We aren’t able to control these groups alone.”
Some polls in Mexico show support for U.S. help, including even the deployment of troops, which won’t be politically workable with the current government. Its critics are trying to nudge the option on the table.
What’s indisputable is that this isn’t only the Mexicans’ problem.”
“From the perspective of drug traffickers, fentanyl has several advantages over heroin. It is much more potent, which makes it easier to smuggle, and it can be produced much more cheaply and inconspicuously, since it does not require opium poppies. Xylazine has similar advantages: It is an inexpensive synthetic drug that can be produced without crops. And unlike fentanyl, it is not classified as a controlled substance, which makes it easier to obtain.
American drug users are not clamoring for xylazine in their fentanyl, any more than they were demanding fentanyl instead of heroin. The use of such adulterants is driven by the economics of prohibition. And as usual with illegal drugs, consumers do not know what they are getting. Whether it is vitamin E acetate in black market THC vapes, MDMA mixed with butylone, levamisole in cocaine, or fentanyl pressed into ersatz pain pills, prohibition reliably makes drug use more dangerous.
Much to the dismay of veterinarians, drug warriors alarmed by tranq have proposed treating xylazine as a controlled substance. As usual, they think the solution to a problem created by prohibition is more prohibition.”
“When governments try to stop people from consuming politically disfavored intoxicants, they make consumption of those substances more dangerous by creating a black market in which purity and potency are highly variable and unpredictable.”
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“Iran’s ban on alcohol consumption by Muslims forces drinkers to rely on illicit sources that sell iffy and possibly poisonous liquor. In a legal market, people who buy distilled spirits do not have to worry about methanol contamination.”
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“Fentanyl is much more potent than heroin, so it is easier to smuggle, and can be produced much more cheaply and inconspicuously since it does not require opium poppies. Xylazine has similar advantages: It is an inexpensive synthetic drug that can be produced without crops. And unlike fentanyl, it is not classified as a controlled substance, so it is easier to obtain.
The emergence of fentanyl as a heroin booster and substitute made potency even harder to predict. The consequences can be seen in record numbers of drug-related deaths.
The government aggravated that situation by restricting the supply of legally produced, reliably dosed opioids, which drove nonmedical users toward more dangerous substitutes and left bona fide patients to suffer from unrelieved pain.”