Tag: research

“Prior to COVID-19, Fauci had long supported funding pandemic research that other scientists found risky, if not downright dangerous.
In 2005, as NIAID director, he praised researchers who’d used a grant from his agency to resurrect the virus that had caused the Spanish flu pandemic. Better understanding that virus would help prevent future diseases, he argued. “The certain benefits to be obtained by a robust and responsible research agenda aimed at developing the means to detect, prevent and treat [future pandemics] far outweigh any theoretical risks,” he said in an October 2005 statement co-authored with then–CDC Director Julie Gerberding.

This wasn’t a universal opinion at the NIAID. The agency’s chief scientist described this approach to pandemic prevention as “looking for a gas leak with a lighted match.”

Fauci would continue to praise and fund this kind of research. In 2011, researchers at the University of Wisconsin and at Erasmus University Medical Center in the Netherlands managed to manipulate the virus H5N1 (which had been responsible for a 2004 bird flu epidemic in Asia) to transmit between mammals, a “gain of function” for a virus that had heretofore only been able to pass from infected birds to humans. One of the researchers involved in the work would say the enhanced pathogen they’d created was “very, very bad news” and “probably one of the most dangerous viruses you can make.” Fauci was more sanguine, telling The New York Times that “there is always a risk. But I believe the benefits are greater than the risks.””

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“In 2014, there was a series of embarrassing safety lapses at U.S. government labs, highlighting this risk.

Dozens of CDC employees were potentially exposed to live anthrax samples shipped by mistake to labs not equipped to handle them. At another CDC lab, a less dangerous version of bird flu was accidentally contaminated with deadly H5N1. Vials of smallpox capable of infecting people were stashed in a cabinet at an NIH lab, where they’d apparently been sitting for decades. None of these incidents were direct results of gain-of-function research. But they heightened the concern that researchers working to enhance deadly pathogens might do so in unsafe settings.”

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“In 2021, Fauci said the NIH “has not ever and does not now fund gain-of-function research in the Wuhan Institute of Virology.” That wasn’t true. What EcoHealth was doing in Wuhan clearly met the widely understood definition of gain-of-function research.

In his June 2024 testimony, Fauci dodged accusations that he lied by saying that while EcoHealth’s work might have met a generic definition of gain-of-function research, it didn’t meet the precise definition established in the P3CO framework.

Fauci said that every time he mentioned gain-of-function research, “the definition that I use is not my personal definition; it is a codified, regulatory and operative definition.” That definition, he said, “had nothing to do with me.”

On the contrary, regulatory definitions had quite a bit to do with Fauci. They were designed with the expectation that he and his fellow public health bureaucrats would use discretion and good judgment when making decisions. The relevant regulatory language included lots of “likelys and highlys and reasonably anticipated,” says Gerald Epstein, a former director at the White House Office of Science and Technology Policy who wrote the P3CO policy. “These words are inherently subjective. You can’t not be. You’ve got to be making judgment calls on something that does not yet exist.” Those subjective definitions gave Fauci and his NIAID underlings considerable room to decide what research required additional review.”

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“We probably won’t ever definitively discover the origins of COVID-19.”

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“Chinese officials obstructed any investigation into the Wuhan Institute of Virology. In September 2019, the Associated Press reported, the institute took its database of viruses offline. It also hasn’t made public lab notebooks and other materials that might shed light on exactly what kinds of work it was doing in the lead-up to the pandemic. In late 2019, the Chinese government also exterminated animals and disinfected the Wuhan wet market. If COVID did leap from animal to human in the Wuhan market, as many natural origin proponents argue, that evidence is gone.

What we’re left with is studying the structure of the SARS-CoV-2 virus itself and whatever information can be gleaned from the U.S.-funded research that went on at Wuhan leading up to the pandemic.

On both fronts, Fauci, his underlings at the NIAID, and NIAID-funded scientists involved with work at Wuhan have worked to conceal information and discredit notions that COVID might have leaked from a lab.

In late January 2020, Fauci’s aides flagged the NIAID’s support of EcoHealth’s Wuhan research in emails to their boss. A few weeks later, Fauci and Daszak would go on Newt Gingrich’s podcast to dismiss the idea that COVID-19 came from the Wuhan lab, calling such arguments “conspiracy theories.”

Both men also worked to shape the discourse behind the scenes away from any focus on a lab leak. Daszak organized a group letter of scientists in The Lancet, the U.K.’s top medical journal, declaring that they “stand together to strongly condemn conspiracy theories suggesting that COVID-19 does not have a natural origin.” Daszak did not disclose his relationship to the Wuhan lab when organizing this letter; The Lancet’s editor would eventually concede that this was improper.

In testimony to the House coronavirus subcommittee in May 2024, Daszak would claim the “conspiracy theories” mentioned in the Lancet letter referred only to such wild early pandemic notions that COVID had pieces of HIV or snake DNA inserted into it. He said a word limit prevented him from being more precise.

Fauci, meanwhile, would help corral virologists into publishing the widely cited “proximal origin” paper in early 2020. In the paper, the authors flatly declared that “we do not believe any type of laboratory-leak scenario is plausible.”

Yet troves of private messages and emails released by the House subcommittee’s investigation show that the authors privately expressed far more openness to a lab leak theory.

One of the paper’s authors, Scripps Research evolutionary biologist Kristian Andersen, privately rated a lab leak as “highly likely.” But Andersen had a pending $8.9 million grant application with the NIAID as the paper was drafted. That grant was later approved. In an email, one of the paper’s authors, Edward Holmes, references “pressure from on high” during the drafting process.

The authors of the proximal origin paper say they merely had their minds changed while drafting the paper. They were just following the scientific method.”

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“Fauci’s best defense is that he ran a sprawling agency that doled out billions of dollars in grants. Even the most detail-obsessed administrator couldn’t possibly keep track of every single program and project. And U.S. officials had limited control over what happened in the distant, opaque Wuhan lab.

But even if that’s true, it’s an admission of administrative negligence, since the oversight protocols weren’t followed. It also implies a dramatic failure of the risky research that Fauci championed for pandemic prevention. As Ridley says, the pandemic “occurred with the very viruses that there was the most attention paid to, in the very area where there was the most research going on, where there was the biggest program looking for potential pandemic pathogens, and yet they failed to see this one coming.” At a minimum, gain-of-function research didn’t protect the public from the pandemic.

Meanwhile, the more direct case against Fauci is strong: Not only was he an ardent supporter of research widely believed to be risky, but he manipulated bureaucratic protocols in order to avoid scrutiny of that research, then responded evasively when called to account for his actions. At least one of the programs born out of Fauci’s risky research crusade was pursuing exactly the type of viral enhancements that were present in COVID-19, and that research was conducted at the Wuhan virology lab in the very same city where the virus originated. Lab leak proponents cite the virus’s transmissibility as evidence for a Wuhan leak: After all, EcoHealth was trying to create pathogens primed to spread rapidly in humans.

The evidence is not fully conclusive. But it seems reasonably likely that Fauci pushed for what his peers repeatedly said was dangerous research, that some of that dangerous research produced a deadly viral pathogen that escaped the lab, and that Fauci helped cover up evidence and arguments for its origins.”

https://reason.com/2024/09/14/faucis-pandemic/